Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1576095 | 0.89 | GPR119 (0.64) | GPR119KDM4EPKMHDAC1CHEK2 | |
| SCHEMBL7375564 | 0.89 | GPR119 (0.57) | GPR119KDM4EPKMFAAHHDAC1 | |
| SCHEMBL1575733 | 0.84 | GPR119 (0.72) | GPR119KDM4EPKMFAAHCHEK2 | |
| SCHEMBL7376662 | 0.82 | GPR119 (0.70) | GPR119KDM4EPKMFAAHCHEK2 | |
| SCHEMBL1575654 | 0.82 | GPR119 (0.64) | GPR119KDM4EPKMFAAHCHEK2 | |
| SCHEMBL26668533 | 0.81 | KDM4E (0.70) | GPR119KDM4EPKM | |
| SCHEMBL1924373 | 0.80 | GPR119 (0.70) | GPR119FAAH | |
| SCHEMBL7376952 | 0.80 | ITGB3 (0.60) | — | |
| SCHEMBL7405900 | 0.79 | KDM4E (0.57) | GPR119KDM4EPKMHDAC1CHEK2 | |
| SCHEMBL16385072 | 0.78 | GPR119 (0.67) | GPR119KDM4EPKMCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563158-A | CARDIOVASCULAR DISORDERS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| WO-1995018111-A1 | COMPOUNDS CONTAINING BASIC AND ACIDIC TERMINI USEFUL AS FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-06 | — | — | WO | disclosed |