Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14621456 | 0.86 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL9215011 | 0.81 | ITGB3 (0.57) | ITGB3ITGA2B | |
| SCHEMBL12735814 | 0.81 | PLK1 (0.56) | ITGB3ITGA2B | |
| SCHEMBL12718932 | 0.81 | ITGB3 (0.63) | ITGB3ITGA2B | |
| SCHEMBL7372423 | 0.80 | GPR119 (0.61) | — | |
| SCHEMBL833572 | 0.78 | POLB (0.53) | ITGB3ITGA2B | |
| SCHEMBL7739629 | 0.78 | NPC1 (0.67) | MAPK1 | |
| SCHEMBL12735798 | 0.77 | ITGB3 (0.58) | ITGB3ITGA2B | |
| SCHEMBL2555567 | 0.77 | ITGB3 (0.62) | ITGB3ITGA2B | |
| SCHEMBL14621457 | 0.76 | ITGB3 (0.50) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563158-A | CARDIOVASCULAR DISORDERS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| WO-1995018111-A1 | COMPOUNDS CONTAINING BASIC AND ACIDIC TERMINI USEFUL AS FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-06 | — | — | WO | disclosed |