Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329598 | 0.82 | KDM4E (0.41) | KDM4EGPR3EGFRCYP1A2MGAM | |
| SCHEMBL637363 | 0.81 | CA1 (0.45) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL31387787 | 0.81 | ALDH1A1 (0.41) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL30925390 | 0.77 | L3MBTL1 (0.42) | L3MBTL1KDM4EGPR3EGFRCYP1A2 | |
| SCHEMBL27709182 | 0.77 | CYP1A2 (0.41) | L3MBTL1KDM4EGPR3EGFRCYP1A2 | |
| SCHEMBL7736717 | 0.77 | LMNA (0.37) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL27372062 | 0.74 | KDM4E (0.42) | L3MBTL1KDM4ECYP1A2ALDH1A1MAPT | |
| SCHEMBL3531193 | 0.73 | KDM4E (0.53) | L3MBTL1KDM4ECYP1A2HDAC8ALDH1A1 | |
| SCHEMBL27974064 | 0.73 | ALDH1A1 (0.49) | L3MBTL1KDM4EGPR3EGFRCYP1A2 | |
| SCHEMBL27930768 | 0.73 | KDM4E (0.54) | L3MBTL1KDM4EALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977169-A | FOR TREATMENT OF A PERSON WITH AIDS OR AIDS RELATED DISEASES | PHARMACIA & UPJOHN COMPANY | 1999-11-02 | — | — | US | claimed |
| EP-0720607-A1 | SUBSTITUTED TETRONIC ACIDS USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1996-07-10 | — | — | EP | claimed |
| WO-1995007901-A1 | SUBSTITUTED TETRONIC ACIDS USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | THE UPJOHN COMPANY (US) | 1995-03-23 | — | — | WO | claimed |
| CN-114384164-A | Aminoglycoside antibiotic aptamer, affinity column thereof, preparation method and application thereof | 北京市农林科学院 | 2022-04-22 | — | — | CN | disclosed |
| CN-104130167-A | 3-[(dodecamercapto)(propyl)methyl]pentyl-2,4-dione synthesis method | ANHUI SHIHUA CHEMICAL CO LTD | 2014-11-05 | — | — | CN | disclosed |
| CN-102260217-B | 2-sulfo-quinazoline derivative and synthesis method | HUAIHAI INST TECHNOLOGY | 2014-03-05 | — | — | CN | disclosed |
| CN-102260217-B | 2-sulfo-quinazoline derivative and synthesis method | HUAIHAI INST TECHNOLOGY | 2014-03-05 | — | — | CN | disclosed |
| CN-102260217-A | 2-sulfo-quinazoline derivative and synthesis method | — | 2011-11-30 | — | — | CN | disclosed |
| CN-102260217-A | 2-sulfo-quinazoline derivative and synthesis method | — | 2011-11-30 | — | — | CN | disclosed |
| CN-1246034-A | Fungicidal mixtures | DU PONT (US) | 2000-03-01 | — | — | CN | disclosed |
| US-5977169-A | FOR TREATMENT OF A PERSON WITH AIDS OR AIDS RELATED DISEASES | PHARMACIA & UPJOHN COMPANY | 1999-11-02 | — | — | US | disclosed |
| EP-0720607-A1 | SUBSTITUTED TETRONIC ACIDS USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1996-07-10 | — | — | EP | disclosed |
| CN-1123028-A | Fungicidal fused bicyclic pyrimidinones | DU PONT (US) | 1996-05-22 | — | — | CN | disclosed |
| WO-1995007901-A1 | SUBSTITUTED TETRONIC ACIDS USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | THE UPJOHN COMPANY (US) | 1995-03-23 | — | — | WO | disclosed |