Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAP2 | P11137 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CSF1R | P07333 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384138 | 0.89 | HPGD (0.64) | ALDH1A1MAP2HPGDCYP1A2CYP2C19 | |
| SCHEMBL7382592 | 0.88 | MEN1 (0.57) | ALDH1A1HPGDCYP1A2CYP2C19MAPT | |
| SCHEMBL7382844 | 0.87 | MEN1 (0.47) | ALDH1A1HPGDCYP1A2CYP2C19MAPT | |
| SCHEMBL7378997 | 0.87 | GABRA1 (0.56) | ALDH1A1HPGDCYP1A2CYP2C19PLA2G2A | |
| SCHEMBL7381494 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MAP2HPGDCYP1A2CYP2C19 | |
| SCHEMBL7381826 | 0.86 | MAPT (0.53) | ALDH1A1HPGDCYP1A2CYP2C19MAPT | |
| SCHEMBL7378603 | 0.86 | GABRA1 (0.45) | ALDH1A1HPGDCYP1A2CYP2C19MAPT | |
| SCHEMBL7381444 | 0.83 | GABRA1 (0.48) | ALDH1A1HPGDCYP1A2CYP2C19MAPT | |
| SCHEMBL7381272 | 0.77 | GABRA1 (0.57) | ALDH1A1HPGDCYP1A2CYP2C19XBP1 | |
| SCHEMBL7383581 | 0.77 | GABRA1 (0.71) | ALDH1A1HPGDCYP1A2CYP2C19XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010077-A | Tranquilizers | A/S FERROSAN (DK) | 1991-04-23 | — | — | US | disclosed |
| EP-0030254-B1 | BETA-CARBOLIN-3-CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR THERAPEUTICAL USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-10-31 | — | — | EP | disclosed |
| US-4371536-A | TRANQUILIZERS | A/S FERROSAN (DK) | 1983-02-01 | — | — | US | disclosed |
| EP-0030254-A1 | Beta-carbolin-3-carboxylic acid derivatives, pharmaceutical compositions containing them and their therapeutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-06-17 | — | — | EP | disclosed |