Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.57 |
| ▸ | MMP1 | P03956 | 12/20 | 0.57 |
| ▸ | MMP12 | P39900 | 2/20 | 0.57 |
| ▸ | MMP13 | P45452 | 2/20 | 0.57 |
| ▸ | MMP9 | P14780 | 11/20 | 0.54 |
| ▸ | MMP3 | P08254 | 8/20 | 0.54 |
| ▸ | MMP8 | P22894 | 5/20 | 0.54 |
| ▸ | MMP7 | P09237 | 4/20 | 0.54 |
| ▸ | FCER2 | P06734 | 3/20 | 0.54 |
| ▸ | MMP14 | P50281 | 5/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424672 | 0.84 | MMP2 (0.50) | MMP2MMP1MMP12MMP13MMP9 | |
| SCHEMBL14068117 | 0.77 | MMP2 (0.66) | MMP2MMP1MMP12MMP13MMP9 | |
| SCHEMBL3842681 | 0.75 | TAAR1 (0.48) | MMP1MMP3 | |
| SCHEMBL8777260 | 0.75 | MMP2 (0.55) | MMP2MMP1MMP9MMP3MMP7 | |
| SCHEMBL10424074 | 0.75 | MMP1 (0.51) | MMP2MMP1MMP12MMP13MMP9 | |
| SCHEMBL29838142 | 0.73 | MMP2 (1.00) | MMP2MMP1MMP12MMP13MMP9 | |
| SCHEMBL4634581 | 0.73 | MMP2 (1.00) | MMP2MMP1MMP12MMP13MMP9 | |
| SCHEMBL4634587 | 0.73 | MMP2 (1.00) | MMP2MMP1MMP12MMP13MMP9 | |
| SCHEMBL4634577 | 0.73 | MMP2 (1.00) | MMP2MMP1MMP12MMP13MMP9 | |
| SCHEMBL7072801 | 0.73 | MMP2 (0.56) | MMP2MMP1MMP12MMP13MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740652-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995019956-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |