Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.56 |
| ▸ | MMP9 | P14780 | 8/20 | 0.56 |
| ▸ | MMP1 | P03956 | 7/20 | 0.56 |
| ▸ | MMP8 | P22894 | 6/20 | 0.56 |
| ▸ | FCER2 | P06734 | 4/20 | 0.56 |
| ▸ | MMP7 | P09237 | 3/20 | 0.56 |
| ▸ | MMP3 | P08254 | 3/20 | 0.56 |
| ▸ | MMP12 | P39900 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070491 | 0.88 | MMP2 (0.42) | MMP2MMP9MMP1MMP8FCER2 | |
| SCHEMBL7069869 | 0.74 | MMP3 (0.47) | MMP2MMP9MMP1MMP8MMP3 | |
| SCHEMBL7073422 | 0.74 | MMP2 (0.50) | MMP2MMP9MMP1MMP8FCER2 | |
| SCHEMBL7373357 | 0.73 | MMP2 (0.57) | MMP2MMP9MMP1MMP8FCER2 | |
| SCHEMBL14068117 | 0.72 | MMP2 (0.66) | MMP2MMP9MMP1MMP8FCER2 | |
| SCHEMBL5502507 | 0.72 | MMP2 (1.00) | MMP2MMP9MMP1MMP8FCER2 | |
| SCHEMBL7983204 | 0.72 | MMP1 (0.58) | MMP2MMP9MMP1MMP8FCER2 | |
| SCHEMBL7983199 | 0.72 | MMP1 (0.58) | MMP2MMP9MMP1MMP8FCER2 | |
| SCHEMBL6271207 | 0.68 | MMP9 (0.72) | MMP2MMP9MMP1MMP8FCER2 | |
| SCHEMBL10424074 | 0.68 | MMP1 (0.51) | MMP2MMP9MMP1MMP8FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | disclosed |