Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370750 | 0.87 | ALDH1A1 (0.47) | MAPTTDP1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7374234 | 0.87 | MAPT (0.44) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL7338638 | 0.85 | MAPT (0.46) | MAPTALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL7347643 | 0.83 | RXRA (0.44) | MAPTALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL7373593 | 0.83 | ALDH1A1 (0.43) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL7376935 | 0.83 | ALDH1A1 (0.43) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL7344542 | 0.82 | MAPT (0.48) | MAPTALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL7345680 | 0.81 | ALDH1A1 (0.43) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL7377386 | 0.81 | MAPT (0.45) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7426436 | 0.81 | MAPT (0.43) | MAPTALDH1A1LMNAL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |