Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373593 | 0.93 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AGAALMNA | |
| SCHEMBL7338369 | 0.91 | TNF (0.42) | ALDH1A1KDM4EKMT2AGAALMNA | |
| SCHEMBL7376935 | 0.89 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AGAALMNA | |
| SCHEMBL7335732 | 0.87 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2ALMNAMAPT | |
| SCHEMBL7371731 | 0.85 | KDM4E (0.51) | ALDH1A1KDM4EKMT2AGAALMNA | |
| SCHEMBL7344698 | 0.85 | ALDH1A1 (0.40) | ALDH1A1KDM4EKMT2AGAALMNA | |
| SCHEMBL7344542 | 0.84 | MAPT (0.48) | ALDH1A1KDM4EKMT2ALMNAMAPT | |
| SCHEMBL7476833 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2ALMNAMAPT | |
| SCHEMBL7480971 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KDM4EKMT2AGAALMNA | |
| SCHEMBL7347643 | 0.83 | RXRA (0.44) | ALDH1A1KDM4EKMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |