Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370311 | 0.82 | L3MBTL1 (0.43) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7377084 | 0.77 | ALDH1A1 (0.71) | KMT2AALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL7737054 | 0.73 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL20545868 | 0.73 | KMT2A (0.49) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8812280 | 0.73 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL306161 | 0.73 | POLB (0.81) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL7375652 | 0.72 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2451415 | 0.72 | MAPT (0.50) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7375065 | 0.72 | CRHBP (0.52) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| Iodide SCHEMBL22235392 | 0.71 | POLB (0.78) | KMT2AMEN1ALDH1A1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |