Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7276981 | 0.99 | NR1D1 (0.48) | NR1D1ALOX5HTR1ASIGMAR1SMN1; SMN2 | |
| SCHEMBL7284699 | 0.88 | ALOX5 (0.50) | NR1D1ALOX5HTR1ASIGMAR1SMN1; SMN2 | |
| SCHEMBL7286538 | 0.85 | ALOX5 (0.49) | NR1D1ALOX5HTR1ASIGMAR1SMN1; SMN2 | |
| SCHEMBL9531443 | 0.84 | ALOX5 (0.45) | NR1D1ALOX5HTR1ASIGMAR1SMN1; SMN2 | |
| SCHEMBL2546741 | 0.81 | ALOX5 (0.54) | ALOX5HTR1ASIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2546737 | 0.81 | ALOX5 (0.54) | ALOX5HTR1ASIGMAR1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2550091 | 0.80 | ALOX5 (0.52) | ALOX5HTR1ASMN1; SMN2ALDH1A1CA2 | |
| SCHEMBL7275192 | 0.77 | ALOX5 (0.41) | NR1D1ALOX5HTR1ASIGMAR1SMN1; SMN2 | |
| SCHEMBL4958489 | 0.76 | LTA4H (0.48) | LTA4H | |
| Domoxin SCHEMBL2109165 | 0.76 | ALOX5 (0.55) | ALOX5HTR1ASIGMAR1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220735-A2 | 3(2H)-pyridazinone derivatives, a process and intermediates for preparing them and medicaments containing them and/or other 3(2H)-pyridazinone derivatives | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1987-05-06 | — | — | EP | disclosed |