Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAP2K4 | P45985 | 4/20 | 0.51 |
| ▸ | TTK | P33981 | 3/20 | 0.49 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638951 | 0.92 | GAA (0.50) | GAAMAP2K4TTKPRKAB2PRKAG1 | |
| SCHEMBL4791540 | 0.81 | KDM4E (0.59) | GAAMAP2K4TTKEPHB3 | |
| SCHEMBL1967918 | 0.81 | GPR17 (0.43) | MAP2K4PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL28497966 | 0.81 | PARP1 (0.45) | MAP2K4PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL28503102 | 0.79 | PARP1 (0.44) | MAP2K4PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL570533 | 0.79 | HAO1 (0.50) | MAP2K4HCAR2 | |
| SCHEMBL16240884 | 0.79 | CTNNB1 (0.44) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| Hydrochloric Acid SCHEMBL9444673 | 0.78 | HAO1 (0.49) | MAP2K4HCAR2 | |
| SCHEMBL2071431 | 0.77 | KDM4E (0.55) | GAAMAP2K4TTKPBRM1EPHB3 | |
| SCHEMBL29953412 | 0.77 | CDK2 (0.38) | MAP2K4TTKPRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9737510-B2 | Indazole compounds and a process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-08-22 | — | — | US | claimed |
| CN-111995577-A | Synthetic method of 4-fluoro indazole 3-carbonitrile or derivatives thereof | 上海代为化学科技有限公司 | 2020-11-27 | — | — | CN | disclosed |
| US-5166341-A | Selective antagonist of serotonin 3(5-HT3) receptor | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |
| US-5017573-A | Serotonin receptor antagonist | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0358903-A2 | Indazole-3-carboxylic acid derivatives | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1990-03-21 | — | — | EP | disclosed |