Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | MAP2K4 | P45985 | 4/20 | 0.48 |
| ▸ | TTK | P33981 | 3/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.44 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374273 | 0.92 | GAA (0.54) | GAAPBRM1MAP2K4TTKPRKAB2 | |
| SCHEMBL2071431 | 0.82 | KDM4E (0.55) | GAAPBRM1MAP2K4TTKEPHB3 | |
| SCHEMBL8830103 | 0.81 | CTNNB1 (0.42) | TTKPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL2072624 | 0.79 | KDM4E (0.45) | GAAMAP2K4 | |
| SCHEMBL7304420 | 0.79 | PRKAG1 (0.36) | MAP2K4TTKPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL1967918 | 0.77 | GPR17 (0.43) | MAP2K4PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL28497966 | 0.77 | PARP1 (0.45) | PBRM1MAP2K4PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL9079135 | 0.76 | NPC1 (0.36) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL9078171 | 0.76 | HAO1 (0.37) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL904609 | 0.76 | CYP1A2 (0.48) | CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519140-B1 | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acids, esters and salts thereof, and intermediates used in this method | HYBRINOVA (FR) | 1998-07-29 | — | — | EP | disclosed |
| US-5304672-A | Intermediates for pollen suppressants | ORSAN (FR) | 1994-04-19 | — | — | US | disclosed |
| US-5183891-A | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation | ORSAN (FR) | 1993-02-02 | — | — | US | disclosed |
| EP-0519140-A1 | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation | HYBRINOVA (FR) | 1992-12-23 | — | — | EP | disclosed |