Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 16/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1652680 | 0.77 | F10 (0.34) | ADORA2AADORA1 | |
| SCHEMBL7550066 | 0.71 | F10 (0.53) | KMT2AADORA2AADORA1 | |
| SCHEMBL6220931 | 0.71 | ADORA2A (0.36) | KMT2AADORA2AADORA1 | |
| SCHEMBL6220929 | 0.68 | MEN1 (0.35) | KMT2AADORA2AADORA1 | |
| SCHEMBL59127 | 0.67 | ACVRL1 (0.49) | FGFR1FGFR3FGFR4 | |
| SCHEMBL5426668 | 0.66 | SELE (0.65) | KMT2AADORA1 | |
| SCHEMBL58590 | 0.66 | FGFR1 (0.43) | FGFR1FGFR3FGFR4 | |
| SCHEMBL15020020 | 0.65 | FGFR1 (0.54) | FGFR1FGFR3FGFR4 | |
| SCHEMBL15020465 | 0.65 | FGFR1 (0.49) | FGFR1FGFR3FGFR4 | |
| SCHEMBL15023895 | 0.65 | FGFR1 (0.44) | FGFR1FGFR3FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051176-A4 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARM PROD INC (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1051176-A1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | Aventis Pharmaceuticals Products Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037304-A1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-07-29 | — | — | WO | disclosed |