Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370387 | 0.86 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL7366322 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL7371109 | 0.75 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL29496946 | 0.73 | MEN1 (0.56) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL5797361 | 0.73 | MEN1 (0.56) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL7374031 | 0.73 | MPO (0.47) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL7370232 | 0.71 | NPY5R (0.55) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL12500710 | 0.70 | S1PR1 (0.59) | ALDH1A1KDM4EMEN1KMT2ADCTPP1 | |
| SCHEMBL31621746 | 0.70 | MEN1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL16576443 | 0.70 | MEN1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |