SCHEMBL8970744

SCHEMBL8970744

CO[C@H]1CCCC[C@]1(Cl)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9556556 1.00 SLC6A4 (0.32) SLC6A4SLC6A3MAPT
SCHEMBL8970157 0.94 CYP1A2 (0.30)
SCHEMBL8970085 0.94 CYP1A2 (0.30)
SCHEMBL6025947 0.75 EPHX1 (0.33) MAPT
SCHEMBL8357700 0.74 KDM4E (0.32) MAPT
SCHEMBL8363486 0.72 CYP2C19 (0.30)
SCHEMBL11819305 0.72 CYP2C19 (0.30)
SCHEMBL7374672 0.71 SLC6A4 (0.31) SLC6A4SLC6A3MAPT
SCHEMBL895754 0.71 GRM4 (0.34)
SCHEMBL29412651 0.70 ARG1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376294-B1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI LTD (JP) 1996-03-13 EP disclosed
US-5370821-A Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed
US-5269965-A Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES (JP) 1993-12-14 US disclosed
EP-0376294-A1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI, LTD. (JP) 1990-07-04 EP disclosed