Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 17/20 | 0.77 |
| ▸ | MMP9 | P14780 | 15/20 | 0.77 |
| ▸ | MMP3 | P08254 | 13/20 | 0.77 |
| ▸ | MMP7 | P09237 | 13/20 | 0.77 |
| ▸ | MMP13 | P45452 | 17/20 | 0.68 |
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1618500 | 0.84 | MMP1 (0.56) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL7370308 | 0.82 | MMP1 (0.74) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL6906972 | 0.81 | MMP1 (0.79) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL14878455 | 0.80 | MMP1 (0.52) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL18153290 | 0.79 | PKM (0.66) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL7685520 | 0.79 | MMP1 (0.60) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL7686447 | 0.79 | MMP1 (0.60) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL2441138 | 0.79 | MMP1 (0.63) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL12659053 | 0.79 | MMP1 (0.62) | MMP1MMP9MMP3MMP7MMP13 | |
| SCHEMBL4035557 | 0.78 | MMP1 (0.62) | MMP1MMP9MMP3MMP7MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923563-A1 | 1,4-HETEROCYCLIC METALLPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008825-A1 | 1,4-HETEROCYCLIC METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |