Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.74 |
| ▸ | MMP3 | P08254 | 10/20 | 0.74 |
| ▸ | MMP7 | P09237 | 9/20 | 0.74 |
| ▸ | MMP9 | P14780 | 8/20 | 0.74 |
| ▸ | MMP13 | P45452 | 8/20 | 0.74 |
| ▸ | MMP2 | P08253 | 1/20 | 0.63 |
| ▸ | MMP8 | P22894 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | PKLR | P30613 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019708 | 0.83 | MMP1 (0.66) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL7375156 | 0.82 | MMP1 (0.77) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL7472679 | 0.81 | MMP1 (0.71) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL7413401 | 0.79 | MMP1 (0.59) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL7051939 | 0.79 | MMP1 (1.00) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL12479656 | 0.78 | MMP1 (0.79) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL29873927 | 0.78 | ALDH1A1 (0.73) | ALDH1A1NPC1LMNA | |
| SCHEMBL6906972 | 0.78 | MMP1 (0.79) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL6346795 | 0.76 | MMP1 (0.94) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL6346800 | 0.76 | MMP1 (0.94) | MMP1MMP3MMP7MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923563-A1 | 1,4-HETEROCYCLIC METALLPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008825-A1 | 1,4-HETEROCYCLIC METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |