Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MTTP | P55157 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374161 | 0.94 | AVPR2 (0.40) | PNLIPLMNAMTTPTP53MAPT | |
| SCHEMBL8813868 | 0.92 | MEN1 (0.37) | PNLIPLMNATP53MAPTHTT | |
| SCHEMBL7374840 | 0.92 | PYGL (0.41) | PNLIPLMNAMTTPMAPTAVPR2 | |
| SCHEMBL7376574 | 0.89 | AVPR2 (0.42) | LMNAMAPTAVPR2ALDH1A1AVPR1A | |
| SCHEMBL7372644 | 0.88 | ALDH1A1 (0.39) | LMNATP53MAPTAVPR2HTT | |
| SCHEMBL7374760 | 0.88 | AVPR2 (0.43) | LMNAMAPTAVPR2ALDH1A1AVPR1A | |
| SCHEMBL7376314 | 0.86 | MTTP (0.42) | MTTPMAPTHTTALDH1A1MEN1 | |
| SCHEMBL7372350 | 0.86 | AVPR2 (0.43) | LMNATP53MAPTAVPR2ALDH1A1 | |
| SCHEMBL7378378 | 0.86 | AVPR2 (0.42) | MTTPAVPR2ALDH1A1AVPR1AMEN1 | |
| SCHEMBL7344313 | 0.86 | MEN1 (0.45) | PNLIPMAPTHTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |