Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | PNLIP | P16233 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MTTP | P55157 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375342 | 0.94 | PNLIP (0.39) | AVPR2AVPR1APNLIPMEN1MAPT | |
| SCHEMBL7376314 | 0.93 | MTTP (0.42) | MEN1MAPTKMT2APOLBHPGD | |
| SCHEMBL7372866 | 0.92 | MAPT (0.42) | AVPR2AVPR1AMEN1MAPTKMT2A | |
| SCHEMBL7370671 | 0.92 | GCGR (0.41) | AVPR2AVPR1APNLIPMEN1MAPT | |
| SCHEMBL7369305 | 0.88 | F10 (0.39) | AVPR2AVPR1AMEN1MAPTKMT2A | |
| SCHEMBL7379386 | 0.86 | CYP1A2 (0.44) | AVPR2AVPR1AMEN1KMT2ACYP2C19 | |
| SCHEMBL7373910 | 0.86 | AVPR2 (0.41) | AVPR2AVPR1AMEN1MAPTKMT2A | |
| SCHEMBL8813868 | 0.85 | MEN1 (0.37) | PNLIPMEN1MAPTKMT2APOLB | |
| SCHEMBL7369948 | 0.85 | MTTP (0.39) | AVPR2AVPR1AHPGDMTTP | |
| SCHEMBL7374840 | 0.85 | PYGL (0.41) | AVPR2AVPR1APNLIPMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |