Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367468 | 0.91 | L3MBTL1 (0.48) | LMNATDP1F10POLBL3MBTL1 | |
| SCHEMBL13033926 | 0.88 | LMNA (0.56) | GAALMNATDP1ATMALDH1A1 | |
| SCHEMBL7836030 | 0.88 | LMNA (0.55) | LMNATDP1F10ALDH1A1POLB | |
| SCHEMBL7365216 | 0.88 | LMNA (0.55) | LMNATDP1F10ALDH1A1POLB | |
| SCHEMBL23221679 | 0.78 | LMNA (0.66) | GAALMNATDP1ATMALDH1A1 | |
| SCHEMBL23221677 | 0.78 | LMNA (0.66) | GAALMNATDP1ATMALDH1A1 | |
| SCHEMBL2633261 | 0.77 | LMNA (0.68) | LMNATDP1ATMALDH1A1POLB | |
| SCHEMBL14527603 | 0.77 | CAPN1 (0.54) | LMNAALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL9208207 | 0.76 | ATM (0.57) | GAALMNAATMALDH1A1THRB | |
| SCHEMBL23221689 | 0.76 | PSMB5 (0.60) | GAALMNATDP1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001974-A1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006434-A1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS INC. (US) | 1999-02-11 | — | — | WO | disclosed |