Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698882 | 0.88 | ADRA2C (0.64) | ADRA2CMEN1KMT2AHPGDNPC1 | |
| SCHEMBL9716677 | 0.85 | ADRA2C (0.53) | ADRA2CMEN1KMT2AHPGDNPC1 | |
| SCHEMBL10660695 | 0.83 | BACE1 (0.52) | ADRA2CMEN1KMT2AHPGDNPC1 | |
| SCHEMBL7375547 | 0.83 | HPGD (0.64) | ADRA2CMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6569544 | 0.83 | PKM (0.56) | ADRA2CMEN1KMT2AHPGDNPC1 | |
| SCHEMBL6174036 | 0.83 | ADRA2C (0.51) | ADRA2CMEN1KMT2AHPGDNPC1 | |
| SCHEMBL10659082 | 0.80 | ADRA2C (0.48) | ADRA2CMEN1KMT2AHPGDNPC1 | |
| SCHEMBL6570858 | 0.80 | KDM4E (0.63) | ADRA2CMEN1KMT2AHPGDNPC1 | |
| SCHEMBL20681717 | 0.80 | RORC (0.60) | ADRA2CMEN1KMT2AHPGDNPC1 | |
| SCHEMBL8725847 | 0.80 | ADRA2C (0.55) | ADRA2CMEN1KMT2AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |