Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.68 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 3/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | HRH1 | P35367 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8054055 | 0.99 | DRD2 (0.67) | DRD2CYP2J2SIGMAR1KMT2AOPRM1 | |
| SCHEMBL11861029 | 0.83 | CYP2J2 (0.94) | CYP2J2HRH1 | |
| Hydrochloric Acid SCHEMBL11866868 | 0.82 | CYP2J2 (0.92) | CYP2J2KMT2AHRH1 | |
| SCHEMBL11865078 | 0.82 | CYP2J2 (0.92) | CYP2J2HRH1 | |
| Hydrochloric Acid SCHEMBL10824127 | 0.81 | DRD2 (0.64) | DRD2CYP2J2SIGMAR1KMT2AMCHR1 | |
| SCHEMBL20652674 | 0.81 | DRD2 (1.00) | DRD2SIGMAR1KMT2AOPRM1HTR1A | |
| Hydrochloric Acid SCHEMBL11867724 | 0.81 | CYP2J2 (0.90) | CYP2J2KMT2AHRH1 | |
| SCHEMBL7375551 | 0.81 | ALDH1A1 (0.59) | DRD2CYP2J2SIGMAR1OPRM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8054053 | 0.80 | ALDH1A1 (0.58) | DRD2CYP2J2SIGMAR1OPRM1HTR7 | |
| SCHEMBL14435454 | 0.79 | ALDH1A1 (0.78) | DRD2KMT2AHTR7HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000131-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | CAMBRIDGE NEUROSCIENCE, INCORPORATED (US) | 1995-01-05 | — | — | WO | disclosed |