Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375594 | 0.86 | KMT2A (0.44) | ALDH1A1MEN1KMT2ANOD2DRD2 | |
| SCHEMBL7372404 | 0.85 | ALDH1A1 (0.55) | ALDH1A1HTTKMT2AABCB1LMNA | |
| SCHEMBL7411521 | 0.85 | ALDH1A1 (0.55) | ALDH1A1HTTMEN1KMT2AABCB1 | |
| SCHEMBL8488927 | 0.78 | FAAH (0.39) | ALDH1A1HTTMEN1KMT2ADRD2 | |
| SCHEMBL7374208 | 0.75 | MEN1 (0.47) | ALDH1A1MEN1KMT2ANOD2LMNA | |
| SCHEMBL7372045 | 0.75 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL8488928 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HTTMEN1KMT2AABCB1 | |
| SCHEMBL7372518 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL7373471 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL7374972 | 0.72 | ALDH1A1 (0.51) | ALDH1A1HTTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706517-B1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL IND LTD (JP) | 1998-10-21 | — | — | EP | disclosed |
| WO-1995001343-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |