Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491622 | 0.84 | CYP2D6 (0.49) | ALDH1A1MEN1KMT2AMAPK1CYP2D6 | |
| SCHEMBL8488933 | 0.80 | FAAH (0.40) | MEN1KMT2AMCHR1POLBFAAH | |
| SCHEMBL8488931 | 0.77 | MCHR1 (0.43) | ALDH1A1MEN1KMT2AMCHR1FAAH | |
| SCHEMBL7375596 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AMCHR1FAAH | |
| SCHEMBL13150429 | 0.70 | FAAH (0.63) | ALDH1A1MEN1KMT2AFAAHCYP2C19 | |
| SCHEMBL8489959 | 0.70 | MCHR1 (0.44) | MCHR1FAAHDRD4SIGMAR1 | |
| SCHEMBL3075662 | 0.69 | TSHR (0.49) | ALDH1A1L3MBTL1CYP2D6TSHRHSD17B10 | |
| SCHEMBL8489951 | 0.68 | FAAH (0.52) | ALDH1A1MEN1KMT2AMCHR1POLB | |
| SCHEMBL8487205 | 0.67 | HSD17B10 (0.57) | ALDH1A1MEN1KMT2AL3MBTL1FAAH | |
| SCHEMBL7375594 | 0.66 | KMT2A (0.44) | ALDH1A1MEN1KMT2AMCHR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929074-A | VSODILATOR, ANTIALLERGIC AND ANTIPLATELET AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| US-5728702-A | BRONCHODILATOR AGENTS, ANTIALLERGENS OR ANTIPLATELET DRUGGS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |