Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384151 | 0.88 | CYP3A4 (0.46) | HRH4MMEECE1CYP3A4CYP2D6 | |
| SCHEMBL7385032 | 0.87 | MME (0.53) | MMEECE1TSHRACE | |
| SCHEMBL7416551 | 0.86 | CYP3A4 (0.44) | HRH4MMEECE1CYP3A4CYP2D6 | |
| SCHEMBL7382521 | 0.85 | CYP3A4 (0.43) | HRH4MMEECE1CYP3A4CYP2D6 | |
| SCHEMBL7377079 | 0.84 | CYP3A4 (0.43) | HRH4MMECYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7383775 | 0.84 | CYP3A4 (0.44) | HRH4MMECYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7386327 | 0.83 | POLB (0.45) | HRH4MMEECE1CYP3A4CYP2D6 | |
| SCHEMBL7381133 | 0.83 | HRH4 (0.52) | HRH4MMEECE1CYP3A4CYP2D6 | |
| SCHEMBL7380749 | 0.82 | POLB (0.48) | CYP3A4CYP2D6CYP2C19MMP8POLB | |
| SCHEMBL7316396 | 0.78 | MME (0.53) | HRH4MMEECE1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853476-A | Phosphorus containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |