Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416551 | 0.91 | CYP3A4 (0.44) | CYP3A4CYP2D6CYP2C19HRH4MMP8 | |
| SCHEMBL7382521 | 0.90 | CYP3A4 (0.43) | CYP3A4CYP2D6CYP2C19HRH4MMP8 | |
| SCHEMBL7383775 | 0.89 | CYP3A4 (0.44) | CYP3A4CYP2D6CYP2C19HRH4MMP8 | |
| SCHEMBL7386327 | 0.88 | POLB (0.45) | CYP3A4CYP2D6CYP2C19HRH4MMP8 | |
| SCHEMBL7375688 | 0.88 | HRH4 (0.46) | CYP3A4CYP2D6CYP2C19HRH4MMP8 | |
| SCHEMBL7380749 | 0.87 | POLB (0.48) | CYP3A4CYP2D6CYP2C19MMP8POLB | |
| SCHEMBL7377079 | 0.87 | CYP3A4 (0.43) | CYP3A4CYP2D6CYP2C19HRH4MMP8 | |
| SCHEMBL7381133 | 0.83 | HRH4 (0.52) | CYP3A4CYP2D6CYP2C19HRH4MME | |
| SCHEMBL7316396 | 0.82 | MME (0.53) | CYP3A4CYP2D6CYP2C19HRH4MMP8 | |
| SCHEMBL5496496 | 0.82 | CYP3A4 (0.50) | CYP3A4CYP2D6CYP2C19HRH4MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853476-A | Phosphorus containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |