Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369850 | 0.92 | RAB9A (0.52) | RAB9ACYP19A1CYP11B1CYP11B2MAPT | |
| SCHEMBL7371110 | 0.84 | PDGFRB (0.46) | RAB9ACYP11B1CYP11B2MAPTCYP1A2 | |
| SCHEMBL7369432 | 0.83 | ABCB1 (0.41) | RAB9ACYP19A1CYP11B1CYP11B2MAPT | |
| SCHEMBL7371561 | 0.83 | PDE2A (0.56) | RAB9ACYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL5594741 | 0.82 | CA12 (0.48) | CYP1A2CYP3A4MKNK1MKNK2PDGFRB | |
| Hydrochloric Acid SCHEMBL7370882 | 0.82 | PDE2A (0.55) | RAB9ACYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL7370258 | 0.82 | MKNK1 (0.46) | CYP19A1CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL7365284 | 0.81 | PDGFRB (0.51) | RAB9ACYP11B1CYP11B2MAPTCYP1A2 | |
| SCHEMBL7370676 | 0.80 | PDGFRB (0.41) | CYP19A1CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL7374146 | 0.80 | PDGFRB (0.43) | CYP11B1CYP11B2CYP1A2CYP3A4MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |