Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375757 | 0.92 | RAB9A (0.52) | RAB9AMAPTNPSR1TDP1KMT2A | |
| SCHEMBL7369432 | 0.83 | ABCB1 (0.41) | RAB9AMAPTNPSR1TDP1KMT2A | |
| SCHEMBL6219958 | 0.82 | CYP19A1 (0.57) | RAB9ATDP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7376120 | 0.82 | MAPT (0.47) | RAB9AMAPTNPSR1HTTSMN1; SMN2 | |
| SCHEMBL7370256 | 0.82 | AMY1A (0.46) | KMT2AMEN1CYP3A4SMN1; SMN2AMY1A | |
| SCHEMBL7365284 | 0.81 | PDGFRB (0.51) | RAB9AMAPTCYP1A2CYP3A4SMN1; SMN2 | |
| SCHEMBL10564760 | 0.80 | TUBB4A (0.45) | RAB9AMAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL7373890 | 0.80 | PDGFRB (0.44) | LMNACYP1A2CYP3A4CYP19A1CYP11B1 | |
| Hydrochloric Acid SCHEMBL7369410 | 0.79 | PDE5A (0.58) | MAPTNPSR1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10519398 | 0.79 | PDGFRB (0.49) | RAB9AMAPTSMN1; SMN2CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |