Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562369 | 0.87 | USP5 (0.48) | SLC6A3CYP2D6SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL1128830 | 0.73 | SLC6A3 (0.45) | SLC6A3HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9891700 | 0.73 | SLC6A3 (0.40) | SLC6A3HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL31618596 | 0.73 | SLC6A3 (0.56) | SLC6A3HPGDCYP2D6L3MBTL1 | |
| SCHEMBL4566341 | 0.69 | SLC6A3 (0.50) | SLC6A3HPGDSMN1; SMN2PDE4DPDE4A | |
| SCHEMBL1237578 | 0.68 | POLB (0.42) | SLC6A3ALDH1A1 | |
| SCHEMBL26254861 | 0.68 | HSD17B3 (0.82) | HSD17B3HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL11348436 | 0.68 | SLC6A3 (0.50) | SLC6A3HPGDCYP2D6SMN1; SMN2L3MBTL1 | |
| SCHEMBL11464173 | 0.67 | USP5 (0.70) | HSD17B3HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL11465783 | 0.67 | HAO1 (0.60) | HSD17B3HPGDSMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308785-A2 | Dihydropyridine ethers, processes for their preparation and their utilisation | BAYER AG (DE) | 1989-03-29 | — | — | EP | disclosed |