Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128830 | 0.83 | SLC6A3 (0.45) | SLC6A3ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31618596 | 0.83 | SLC6A3 (0.56) | SLC6A3HPGD | |
| SCHEMBL1237578 | 0.78 | POLB (0.42) | SLC6A3POLBALDH1A1 | |
| SCHEMBL11348436 | 0.77 | SLC6A3 (0.50) | SLC6A3HPGDSMN1; SMN2 | |
| SCHEMBL14949943 | 0.76 | SLC18A3 (0.39) | SLC6A3ALDH1A1SLC18A3HPGDSMN1; SMN2 | |
| SCHEMBL7375852 | 0.73 | HSD17B3 (0.42) | SLC6A3ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10562369 | 0.73 | USP5 (0.48) | SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL5238474 | 0.73 | DHODH (0.54) | POLBSLC18A3SMN1; SMN2 | |
| SCHEMBL21363516 | 0.72 | RAB9A (0.38) | SLC6A3ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28416578 | 0.71 | ALDH1A1 (0.34) | SLC6A3POLBALDH1A1SLC18A3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912348-B2 | Tetrahydropyranyl compound and method for producing the tetrahydropyranyl compound | RICOH COMPANY, LTD. (JP) | 2014-12-16 | — | — | US | disclosed |
| WO-2012099181-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2012-07-26 | — | — | WO | disclosed |
| US-20120142948-A1 | TETRAHYDROPYRANYL COMPOUND AND METHOD FOR PRODUCING THE TETRAHYDROPYRANYL COMPOUND | RICOH COMPANY, LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
| US-20120142948-A1 | TETRAHYDROPYRANYL COMPOUND AND METHOD FOR PRODUCING THE TETRAHYDROPYRANYL COMPOUND | RICOH COMPANY, LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142948-A1 | TETRAHYDROPYRANYL COMPOUND AND METHOD FOR PRODUCING THE TETRAHYDROPYRANYL COMPOUND | CYP4A11, CYP11B1, CYP11B2 | SLC6A3 4432/4885POLB 3032/4885ALDH1A1 2275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.