Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.50 |
| ▸ | KMO | O15229 | 2/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31618596 | 0.82 | SLC6A3 (0.56) | SLC6A3EPHX1MEN1KMT2AHPGD | |
| SCHEMBL3939878 | 0.77 | ANPEP (0.50) | KMOANPEPENPEPSMN1; SMN2EPHX1 | |
| SCHEMBL31401130 | 0.77 | ANPEP (0.50) | KMOANPEPENPEPSMN1; SMN2EPHX1 | |
| SCHEMBL11348436 | 0.77 | SLC6A3 (0.50) | SLC6A3SMN1; SMN2EPHX1MEN1KMT2A | |
| SCHEMBL29369652 | 0.74 | SLC6A3 (0.67) | SLC6A3SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL10562369 | 0.72 | USP5 (0.48) | SLC6A3SMN1; SMN2KMT2A | |
| SCHEMBL28779591 | 0.72 | SLC6A3 (0.52) | SLC6A3SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL15563963 | 0.71 | ANPEP (0.44) | KMOANPEPENPEPEPHX1MEN1 | |
| SCHEMBL15846301 | 0.71 | SLC6A3 (0.70) | SLC6A3MEN1KMT2AHPGD | |
| SCHEMBL4566340 | 0.71 | KMO (0.50) | KMOMEN1KMT2AAPEX1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |