Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GPR132 | Q9UNW8 | 6/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.45 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.45 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5832910 | 0.88 | GPR132 (0.54) | ACACBKDM4EGPR132PLGLTA4H | |
| SCHEMBL5832913 | 0.88 | GPR132 (0.54) | ACACBKDM4EGPR132PLGLTA4H | |
| SCHEMBL5832735 | 0.86 | LTA4H (0.61) | KDM4ELTA4HMAPTLNPEP | |
| SCHEMBL2860639 | 0.86 | LTA4H (0.61) | KDM4ELTA4HMAPTLNPEP | |
| SCHEMBL20099522 | 0.86 | CYP1A2 (0.49) | KDM4EALDH1A1MAPTHTT | |
| Hydrochloric Acid SCHEMBL5832752 | 0.85 | LTA4H (0.60) | LTA4HLNPEP | |
| Hydrochloric Acid SCHEMBL5832756 | 0.85 | LTA4H (0.60) | LTA4HLNPEP | |
| SCHEMBL7337394 | 0.83 | ACACB (0.56) | ACACBKDM4EGPR132PLGMMP13 | |
| SCHEMBL7337381 | 0.83 | ACACB (0.56) | ACACBKDM4EGPR132PLGMMP13 | |
| SCHEMBL31688840 | 0.83 | GPR132 (0.61) | ACACBGPR132MMP13MAPK1ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117841-A | USED TO TREAT STROKE, CEREBRAL ISCHEMIA, PAIN, HEAD TRAUMA OR EPILEPSY | WARNER-LAMBERT COMPANY (US) | 2000-09-12 | — | — | US | claimed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | claimed |
| US-6117841-A | USED TO TREAT STROKE, CEREBRAL ISCHEMIA, PAIN, HEAD TRAUMA OR EPILEPSY | WARNER-LAMBERT COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |