Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 10/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376154 | 1.00 | SYK (0.54) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL5060739 | 0.88 | SYK (0.56) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL186698 | 0.88 | SYK (0.56) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL2519866 | 0.86 | CTSK (0.53) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL11127997 | 0.84 | SYK (0.66) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL6320951 | 0.84 | SYK (0.59) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL13688643 | 0.84 | SYK (0.66) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL21340066 | 0.84 | SYK (0.66) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL19485480 | 0.84 | CTSK (0.62) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL4641124 | 0.84 | SYK (0.59) | SYKCTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057314-A | ANTICOAGULANTS | BIOCHEM PHARMA INC. (CA) | 2000-05-02 | — | — | US | disclosed |
| EP-0802916-A1 | LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS | BIOCHEM PHARMA INC (CA) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996019483-A1 | LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS | BIOCHEM PHARMA INC. (CA) | 1996-06-27 | — | — | WO | disclosed |