Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384102 | 0.93 | MAPT (0.56) | KMT2ARAB9AGAAMAPTNAMPT | |
| SCHEMBL7384793 | 0.85 | SMN1; SMN2 (0.54) | KMT2ARAB9AGAAMAPTNAMPT | |
| SCHEMBL7382435 | 0.83 | RAB9A (0.54) | KMT2ARAB9AGAAMAPTNAMPT | |
| SCHEMBL7383783 | 0.80 | SMN1; SMN2 (0.55) | KMT2ARAB9AGAAMAPTNAMPT | |
| SCHEMBL7379939 | 0.80 | MAPT (0.49) | KMT2ARAB9AGAAMAPTSMN1; SMN2 | |
| SCHEMBL7383128 | 0.78 | MAPT (0.53) | KMT2ARAB9AGAAMAPTNAMPT | |
| SCHEMBL7298366 | 0.77 | KMT2A (0.45) | KMT2ARAB9ASMN1; SMN2NPC1TDP1 | |
| SCHEMBL7298373 | 0.77 | KMT2A (0.45) | KMT2ARAB9ASMN1; SMN2NPC1TDP1 | |
| SCHEMBL7381133 | 0.77 | HRH4 (0.52) | KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7381948 | 0.76 | CYP1A2 (0.46) | KMT2ARAB9ANAMPTNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853476-A | Phosphorus containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |