Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384793 | 0.93 | SMN1; SMN2 (0.54) | MAPTNAMPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7376157 | 0.93 | KMT2A (0.57) | MAPTNAMPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7383783 | 0.87 | SMN1; SMN2 (0.55) | MAPTNAMPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7382435 | 0.86 | RAB9A (0.54) | MAPTNAMPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7383128 | 0.85 | MAPT (0.53) | MAPTNAMPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7384120 | 0.83 | MEN1 (0.50) | MAPTNAMPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7376225 | 0.81 | MAPT (0.48) | MAPTNAMPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7379939 | 0.81 | MAPT (0.49) | MAPTSMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL7363583 | 0.81 | RAB9A (0.60) | MAPTNAMPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7370638 | 0.80 | RAB9A (0.57) | MAPTNAMPTSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853476-A | Phosphorus containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |