Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PPIB | P23284 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5388810 | 0.88 | ALDH1A1 (0.42) | MAPTPKMLMNAALDH1A1KMT2A | |
| SCHEMBL8944811 | 0.87 | MAPT (0.49) | MAPTPKMALDH1A1KMT2ARAB9A | |
| SCHEMBL5389244 | 0.84 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL14711764 | 0.81 | F10 (0.47) | LGMNMAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL5922625 | 0.80 | ALDH1A1 (0.46) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL79066 | 0.80 | F10 (0.51) | LGMNLMNACYP1A2CYP3A4MAOA | |
| SCHEMBL2386901 | 0.78 | LGMN (0.46) | LGMNMAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL6543170 | 0.77 | HTT (0.42) | ALDH1A1 | |
| SCHEMBL5390197 | 0.74 | ALDH1A1 (0.41) | MAPTPKMALDH1A1KMT2A | |
| SCHEMBL5408982 | 0.74 | TACR1 (0.57) | MAPTPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0885213-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0885213-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997025323-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |