Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 3/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978313 | 0.82 | BRS3 (0.46) | BRS3AGTR1AGTR2GRIA2GRIA4 | |
| SCHEMBL8357465 | 0.82 | BRS3 (0.45) | BRS3AGTR1AGTR2GRIA2GRIA4 | |
| SCHEMBL3976315 | 0.82 | BRS3 (0.44) | BRS3AGTR1AGTR2GRIA2GRIA4 | |
| SCHEMBL8359615 | 0.79 | BRS3 (0.44) | BRS3AGTR1AGTR2MMEEGLN1 | |
| SCHEMBL12475515 | 0.75 | BRS3 (0.45) | BRS3AGTR1AGTR2GRIA2GRIA4 | |
| SCHEMBL7376271 | 0.73 | ALDH1A1 (0.42) | BRS3AGTR1AGTR2KDM4EALDH1A1 | |
| SCHEMBL9303359 | 0.70 | HPGD (0.39) | BRS3AGTR1AGTR2KDM4EALDH1A1 | |
| SCHEMBL5592930 | 0.70 | BRS3 (0.39) | BRS3KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL8476707 | 0.69 | KDM4E (0.41) | BRS3KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL7376267 | 0.68 | PPARG (0.50) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459136-A1 | Benzimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-12-04 | — | — | EP | disclosed |