Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 6/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475515 | 0.93 | BRS3 (0.45) | BRS3FFAR1AKR1B1AGTR1AGTR2 | |
| SCHEMBL3976315 | 0.91 | BRS3 (0.44) | BRS3FFAR1AKR1B1AGTR1AGTR2 | |
| SCHEMBL5592930 | 0.86 | BRS3 (0.39) | BRS3FFAR1AKR1B1EGLN1 | |
| SCHEMBL3978313 | 0.84 | BRS3 (0.46) | BRS3FFAR1AKR1B1AGTR1AGTR2 | |
| SCHEMBL1775436 | 0.83 | AGTR1 (0.38) | BRS3AGTR1AGTR2 | |
| SCHEMBL7376273 | 0.82 | BRS3 (0.42) | BRS3FFAR1AKR1B1AGTR1AGTR2 | |
| SCHEMBL8359615 | 0.81 | BRS3 (0.44) | BRS3FFAR1AKR1B1AGTR1AGTR2 | |
| SCHEMBL844426 | 0.77 | AGTR1 (0.38) | BRS3AGTR1AGTR2 | |
| SCHEMBL2598197 | 0.76 | XDH (0.38) | BRS3XDH | |
| SCHEMBL6917321 | 0.76 | ABCB11 (0.36) | BRS3AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883111-A | STRONG AND LONG-LASTING ACTION BY ORAL ADMINISTRATION; HYPOTENSIVE AGENTS; CARDIOTONIC AGENTS; ALZHEIMER'S DISEASE; | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-16 | — | — | US | disclosed |