Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489470 | 0.81 | KDM4E (0.60) | MAPK1LTA4HSIGMAR1KMT2AKDM4E | |
| SCHEMBL4324560 | 0.81 | CYP1A2 (0.57) | MAPK1SIGMAR1NPC1RAB9AKMT2A | |
| SCHEMBL29756433 | 0.81 | CYP1A2 (0.57) | MAPK1SIGMAR1NPC1RAB9AKMT2A | |
| SCHEMBL11841171 | 0.81 | CYP1A2 (0.57) | MAPK1SIGMAR1NPC1RAB9AKMT2A | |
| SCHEMBL7369485 | 0.81 | MAPK1 (0.58) | MAPK1HSD17B10SIGMAR1KMT2A | |
| SCHEMBL3436048 | 0.80 | POLB (0.55) | LTA4HSIGMAR1KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL10407517 | 0.80 | APOBEC3A (0.58) | MAPK1SIGMAR1NPC1RAB9AKMT2A | |
| SCHEMBL7372045 | 0.79 | ALDH1A1 (0.54) | MAPK1HSD17B10SIGMAR1KMT2AKDM4E | |
| SCHEMBL14860185 | 0.78 | MAPK1 (0.63) | MAPK1HSD17B10SIGMAR1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8082237 | 0.77 | SIGMAR1 (0.76) | SIGMAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706517-B1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL IND LTD (JP) | 1998-10-21 | — | — | EP | disclosed |
| WO-1995001343-A1 | PYRIDAZINONE DERIVATIVES WITH PHARMACEUTICAL ACTIVITY | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |