Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | CETP | P11597 | 4/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377154 | 1.00 | PPARG (0.43) | PPARGPPARACETPMMP8HPRT1 | |
| SCHEMBL7374937 | 0.92 | MMP9 (0.42) | PPARGPPARACETPMMP8HPRT1 | |
| SCHEMBL7374940 | 0.92 | MMP9 (0.42) | PPARGPPARACETPMMP8HPRT1 | |
| SCHEMBL7382332 | 0.85 | MMP8 (0.44) | PPARGPPARAMMP8HPRT1POLB | |
| SCHEMBL11508717 | 0.84 | CETP (0.43) | PPARGPPARACETPPOLBMMP9 | |
| SCHEMBL7383865 | 0.83 | MMP8 (0.43) | PPARGPPARAMMP8HPRT1POLB | |
| SCHEMBL7383869 | 0.83 | MMP8 (0.43) | PPARGPPARAMMP8HPRT1POLB | |
| SCHEMBL10900739 | 0.80 | CETP (0.45) | CETP | |
| SCHEMBL7364336 | 0.79 | POLB (0.53) | PPARGPPARAMMP8HPRT1POLB | |
| SCHEMBL4116935 | 0.79 | POLB (0.53) | PPARGPPARAMMP8HPRT1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853476-A | Phosphorus containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |