Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | CETP | P11597 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374937 | 1.00 | MMP9 (0.42) | MMP9MMP1MMP3ADAM17ADAM9 | |
| SCHEMBL7377157 | 0.92 | PPARG (0.43) | MMP9MMP1MMP3ADAM17ADAM9 | |
| SCHEMBL7377154 | 0.92 | PPARG (0.43) | MMP9MMP1MMP3ADAM17ADAM9 | |
| SCHEMBL7382332 | 0.87 | MMP8 (0.44) | MMP8PPARGPPARAPOLBCYP1A2 | |
| SCHEMBL7383865 | 0.86 | MMP8 (0.43) | MMP8PPARGPPARAPOLBCYP1A2 | |
| SCHEMBL7383869 | 0.86 | MMP8 (0.43) | MMP8PPARGPPARAPOLBCYP1A2 | |
| SCHEMBL4116935 | 0.81 | POLB (0.53) | MMP8PPARGPPARAPOLBCYP1A2 | |
| SCHEMBL7364336 | 0.81 | POLB (0.53) | MMP8PPARGPPARAPOLBCYP1A2 | |
| SCHEMBL7364337 | 0.81 | POLB (0.53) | MMP8PPARGPPARAPOLBCYP1A2 | |
| SCHEMBL7384954 | 0.77 | ALDH1A1 (0.50) | MMP8POLBCYP1A2HPRT1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853476-A | Phosphorus containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |