Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 7/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782244 | 0.85 | HDAC8 (0.49) | CTSLMEN1KMT2ASMN1; SMN2MMP2 | |
| SCHEMBL7384115 | 0.83 | CAPN1 (0.60) | CAPN1 | |
| SCHEMBL7791340 | 0.83 | CAPN1 (0.60) | CAPN1 | |
| SCHEMBL3904676 | 0.79 | CTSL (0.54) | CTSLMEN1KMT2ASMN1; SMN2MMP2 | |
| SCHEMBL3909187 | 0.78 | CTSL (0.47) | CTSLMEN1KMT2ASMN1; SMN2MMP2 | |
| SCHEMBL7290418 | 0.73 | MMP9 (0.77) | MEN1KMT2AMMP2MMP9MMP7 | |
| SCHEMBL7290422 | 0.73 | MMP9 (0.77) | MEN1KMT2AMMP2MMP9MMP7 | |
| SCHEMBL7790862 | 0.72 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2MMP2MMP9 | |
| SCHEMBL26647406 | 0.72 | CTSL (0.74) | CTSLMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL26647399 | 0.72 | CTSL (0.74) | CTSLMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944584-A1 | BENZAMIDOALDEHYDES AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998023581-A1 | BENZAMIDOALDEHYDES AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-04 | — | — | WO | disclosed |