Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 9/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.55 |
| ▸ | PRNP | P04156 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412581 | 0.82 | ADAM17 (0.48) | NPSR1ALDH1A1KMT2AMEN1ADAM17 | |
| SCHEMBL7415261 | 0.82 | ADAM17 (0.48) | NPSR1ALDH1A1KMT2AMEN1ADAM17 | |
| SCHEMBL6943322 | 0.82 | ADAM17 (0.48) | NPSR1ALDH1A1KMT2AMEN1ADAM17 | |
| SCHEMBL7414486 | 0.81 | POLB (0.46) | ALDH1A1KDM4EHPGDKMT2ARAB9A | |
| SCHEMBL7412762 | 0.75 | NPSR1 (0.43) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7413535 | 0.75 | NPSR1 (0.43) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7412502 | 0.72 | ADAM17 (0.52) | ADAM17 | |
| SCHEMBL7419531 | 0.71 | ADAM17 (0.56) | ALDH1A1KDM4EHPGDADAM17L3MBTL1 | |
| SCHEMBL1613316 | 0.71 | RXFP1 (0.69) | NPSR1RXFP1PRNPALDH1A1KDM4E | |
| SCHEMBL7411846 | 0.70 | ADAM17 (0.42) | NPSR1ALDH1A1KMT2AADAM17MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997042168-A1 | THIO DERIVATIVES OF HYDROXAMIC ACIDS | ZENECA LIMITED (GB) | 1997-11-13 | — | — | WO | disclosed |