Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 8/20 | 0.56 |
| ▸ | MMP1 | P03956 | 5/20 | 0.56 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412762 | 0.78 | NPSR1 (0.43) | MMP1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7413535 | 0.78 | NPSR1 (0.43) | MMP1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7377229 | 0.71 | NPSR1 (0.55) | ADAM17ALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL6943322 | 0.70 | ADAM17 (0.48) | ADAM17ALDH1A1MAPT | |
| SCHEMBL7415261 | 0.70 | ADAM17 (0.48) | ADAM17ALDH1A1MAPT | |
| SCHEMBL7412581 | 0.70 | ADAM17 (0.48) | ADAM17ALDH1A1MAPT | |
| SCHEMBL31407528 | 0.68 | CTSS (0.54) | MMP8MMP2MMP9ALDH1A1KDM4E | |
| SCHEMBL31407521 | 0.68 | CTSS (0.54) | MMP8MMP2MMP9ALDH1A1KDM4E | |
| SCHEMBL8573246 | 0.67 | TSHR (0.42) | ADAM17MMP1MMP2NTSR1ALDH1A1 | |
| SCHEMBL7268353 | 0.66 | MMP8 (0.51) | ADAM17MMP1MMP8MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997042168-A1 | THIO DERIVATIVES OF HYDROXAMIC ACIDS | ZENECA LIMITED (GB) | 1997-11-13 | — | — | WO | disclosed |