Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | FCER2 | P06734 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412762 | 1.00 | NPSR1 (0.43) | NPSR1MEN1KMT2APPARGPPARA | |
| SCHEMBL6943322 | 0.82 | ADAM17 (0.48) | NPSR1MEN1KMT2APOLBMAPT | |
| SCHEMBL7415261 | 0.82 | ADAM17 (0.48) | NPSR1MEN1KMT2APOLBMAPT | |
| SCHEMBL7412581 | 0.82 | ADAM17 (0.48) | NPSR1MEN1KMT2APOLBMAPT | |
| SCHEMBL27471453 | 0.79 | ACE (0.47) | NPSR1POLBMAPTATMTDP1 | |
| SCHEMBL6940090 | 0.79 | ACE (0.47) | NPSR1POLBMAPTATMTDP1 | |
| SCHEMBL7419531 | 0.78 | ADAM17 (0.56) | MAPTALDH1A1MMP1L3MBTL1 | |
| SCHEMBL7377229 | 0.75 | NPSR1 (0.55) | NPSR1MEN1KMT2APOLBMAPT | |
| SCHEMBL6659518 | 0.75 | MMP3 (0.45) | NPSR1MEN1KMT2APPARGPPARA | |
| SCHEMBL6943287 | 0.75 | MMP3 (0.45) | NPSR1MEN1KMT2APPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997042168-A1 | THIO DERIVATIVES OF HYDROXAMIC ACIDS | ZENECA LIMITED (GB) | 1997-11-13 | — | — | WO | disclosed |