Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | NPR3 | P17342 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376786 | 1.00 | CTSK (0.41) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL7376788 | 1.00 | CTSK (0.41) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9401922 | 0.84 | MAPT (0.37) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9401725 | 0.84 | MAPT (0.37) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL10445512 | 0.84 | MAPT (0.37) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9401736 | 0.84 | MAPT (0.37) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9401932 | 0.84 | MAPT (0.37) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL10445510 | 0.84 | MAPT (0.37) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL23260554 | 0.78 | CTSK (0.57) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL11910515 | 0.78 | NPR3 (0.42) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5644059-A | REACTION OF KETONE WITH ACRYLAMIDE AND AMMONIA OR AMMONIUM SALT | FUJIREBIO INC. (JP) | 1997-07-01 | — | — | US | disclosed |
| US-5367081-A | Vasodilator, antiallergen | FUJIREBIO INC. (JP) | 1994-11-22 | — | — | US | disclosed |
| EP-0488345-A1 | 1,4-Dihydropyridine derivatives and methods of producing the same | FUJIREBIO INC. (JP) | 1992-06-03 | — | — | EP | disclosed |