Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382733 | 0.93 | ALDH1A1 (0.45) | ALDH1A1TP53MAPTRAB9ANPC1 | |
| SCHEMBL7380737 | 0.89 | MAPT (0.42) | ALDH1A1TP53MAPTRAB9ANPC1 | |
| SCHEMBL7408424 | 0.89 | ALDH1A1 (0.41) | ALDH1A1TP53MAPTRAB9ANPC1 | |
| SCHEMBL7380572 | 0.88 | ITGB3 (0.40) | ALDH1A1RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL7409600 | 0.87 | MAPT (0.42) | ALDH1A1TP53MAPTRAB9ANPC1 | |
| SCHEMBL7377950 | 0.85 | ALDH1A1 (0.39) | ALDH1A1TP53MAPTRAB9ANPC1 | |
| SCHEMBL7380439 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TP53MAPTRAB9ANPC1 | |
| SCHEMBL7379500 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TP53MAPTRAB9ANPC1 | |
| SCHEMBL7375593 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL7384420 | 0.82 | ALDH1A1 (0.40) | ALDH1A1TP53MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036859-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |