Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409600 | 0.92 | MAPT (0.42) | ALDH1A1RAB9ALMNANR1H4MEN1 | |
| SCHEMBL7466483 | 0.92 | NPC1 (0.45) | ALDH1A1ITGB3ITGA2BRAB9ANR1H4 | |
| SCHEMBL7410381 | 0.91 | ITGB3 (0.41) | ITGB3ITGA2BLMNANR1H4MEN1 | |
| SCHEMBL7410551 | 0.91 | ITGB3 (0.41) | ITGB3ITGA2BLMNANR1H4MEN1 | |
| SCHEMBL7382269 | 0.90 | NR1H4 (0.41) | ALDH1A1ITGB3ITGA2BRAB9ALMNA | |
| SCHEMBL7380572 | 0.89 | ITGB3 (0.40) | ALDH1A1ITGB3ITGA2BRAB9ALMNA | |
| Phenylalanine SCHEMBL7414620 | 0.87 | SLC7A5 (0.47) | ALDH1A1ITGB3ITGA2BRAB9ASMN1; SMN2 | |
| SCHEMBL7382733 | 0.86 | ALDH1A1 (0.45) | ALDH1A1RAB9ALMNANR1H4MEN1 | |
| SCHEMBL7376793 | 0.86 | RAB9A (0.38) | ALDH1A1HPGDITGB3ITGA2BRAB9A | |
| SCHEMBL7375609 | 0.85 | ALDH1A1 (0.39) | ALDH1A1HPGDITGB3ITGA2BRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036859-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |