Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27340876 | 0.77 | MAOA (0.48) | MAOAMAOBHTTTP53ACSL1 | |
| SCHEMBL7325719 | 0.76 | MAOA (0.52) | MAOAMAOBACSL1ALDH1A1MAPK1 | |
| SCHEMBL17820806 | 0.76 | MEN1 (0.40) | HTTTP53NPC1RAB9AALDH1A1 | |
| SCHEMBL8961832 | 0.74 | MAOA (0.48) | MAOAMAOBACSL1 | |
| SCHEMBL15847696 | 0.73 | MAOA (0.47) | MAOAMAOBACSL1HDAC4HDAC7 | |
| SCHEMBL7376388 | 0.73 | ALOX5 (0.47) | HTTTP53 | |
| SCHEMBL27883628 | 0.73 | MAOA (0.47) | MAOAMAOBACSL1 | |
| SCHEMBL13777196 | 0.72 | MAOA (0.73) | MAOAMAOBACSL1NPC1RAB9A | |
| SCHEMBL4668382 | 0.72 | PARP1 (0.53) | MAOAMAOBTP53ALDH1A1MAPT | |
| SCHEMBL1672615 | 0.72 | MAOA (0.59) | MAOAMAOBNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995031449-A1 | NOVEL 3,5-DIMETHYLPIPERIDIN-1-YLALKYL ESTERS | SANOFI (FR) | 1995-11-23 | — | — | WO | disclosed |