Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 12/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7555425 | 0.77 | XIAP (0.44) | XIAPBIRC2TAAR1 | |
| SCHEMBL28216257 | 0.73 | CYP1A2 (0.36) | ABCB1HPGDS | |
| SCHEMBL27710732 | 0.72 | HPGDS (0.37) | HPGDS | |
| SCHEMBL26678642 | 0.71 | PI4KB (0.38) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL162380 | 0.70 | HPGDS (0.38) | ABCB1HPGDS | |
| SCHEMBL17716411 | 0.70 | HPGDS (0.47) | ABCB1HPGDS | |
| SCHEMBL29225400 | 0.69 | GRM5 (0.41) | ABCB1HPGDS | |
| SCHEMBL9481637 | 0.69 | GSK3B (0.37) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL10846586 | 0.66 | ABCB1 (0.32) | ABCB1 | |
| SCHEMBL10846580 | 0.66 | ABCB1 (0.32) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022313-A1 | RENIN INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-12-23 | — | — | WO | disclosed |